Ab Initio Protein Structure Prediction Using Evolutionary Approach: A Survey

Protein Structure Prediction (PSP) problem is to determine the three-dimensional structure of a protein only from its primary structure. Misfolding causes human diseases. Thus, knowledge and functionality proteins, combined with prediction their complex challenge for area computational biology. The metaheuristic optimization algorithms are naturally applicable support in solving NP-hard problems.These bio-inspired, since they were designed based on procedures found nature, such as successful evolutionary behavior natural systems. In this paper, we present survey methods approach \textit{ab initio} computing algorithms, considering both single multi-objective optimization. An overview works presented, some details about which characteristics considered, well specific points used. A comparison between approaches presented directions research field pointed out.